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C: Classification of melanoma cells by phenotype-specific MMP1, MMP3, and CYR61 gene expression according to Widmer et al., 2012 [83]

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Other potential DILI biomarkers under investigation include high-mobility group protein B1 (HMGB-1), a nuclear protein released during necrosis, and the ratio of cleaved to full-length cytokeratin [72]

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